Advances in environmental epidemiology
Identifieur interne : 001E62 ( Main/Exploration ); précédent : 001E61; suivant : 001E63Advances in environmental epidemiology
Auteurs : Caroline M. Tanner [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2010.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Animals, Disease Models, Animal, Environment, Epidemiology, Health Status, Humans, Nervous system diseases, Neuroprotective Agents (therapeutic use), Parkinson Disease (drug therapy), Parkinson Disease (epidemiology), Parkinson Disease (etiology), Parkinson Disease (genetics), Parkinson disease, Parkinson's disease, Risk Factors, complex disease, environment, epidemiology.
- MESH :
- chemical , therapeutic use : Neuroprotective Agents.
- drug therapy : Parkinson Disease.
- epidemiology : Parkinson Disease.
- etiology : Parkinson Disease.
- genetics : Parkinson Disease.
- Animals, Disease Models, Animal, Environment, Health Status, Humans, Risk Factors.
Abstract
Parkinson's disease (PD) is likely due to the combined effects of environment and genes in most cases. Environmental factors inversely associated with PD (or, putative protective factors) include cigarette smoking, use of coffee/caffeine, higher uric acid levels, and anti‐inflammatory drug use. Less well‐established inverse associations with PD include higher cholesterol levels, statin use, higher dietary vitamin B6, and night shift work. Putative risk factors are pesticide exposure, head trauma, certain occupations, and milk consumption. The pathogenesis of PD may begin decades before motor symptoms. PD may have shared determinants with other neurodegenerative disorders involving abnormal protein aggregation. © 2010 Movement Disorder Society
Url:
DOI: 10.1002/mds.22721
Affiliations:
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Le document en format XML
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Environmental factors inversely associated with PD (or, putative protective factors) include cigarette smoking, use of coffee/caffeine, higher uric acid levels, and anti‐inflammatory drug use. Less well‐established inverse associations with PD include higher cholesterol levels, statin use, higher dietary vitamin B6, and night shift work. Putative risk factors are pesticide exposure, head trauma, certain occupations, and milk consumption. The pathogenesis of PD may begin decades before motor symptoms. PD may have shared determinants with other neurodegenerative disorders involving abnormal protein aggregation. © 2010 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li></region></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Tanner, Caroline M" sort="Tanner, Caroline M" uniqKey="Tanner C" first="Caroline M." last="Tanner">Caroline M. 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